- Concept UI
- M0356369
- Registry Numbers
- 0
- Scope Note
- The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHELIAL GROWTH FACTORS. Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as tumor angiogenesis factor and vascular permeability factor. Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating VASODILATION via NITRIC OXIDE-dependent pathways. Alternative splicing of the mRNA for vascular endothelial growth factor A results in several isoforms of the protein being produced.
- Terms
-
Vascular Endothelial Growth Factor A
Preferred Term
Term UI
T406107
Date01/31/2000
LexicalTag
NON
ThesaurusID
NLM (2004)
-
Vascular Endothelial Growth Factor
Term UI
T087222
Date01/01/1955
LexicalTag
NON
ThesaurusID
NLM (2004)
-
Vascular Endothelial Growth Factor-A
Term UI
T526412
Date11/20/2002
LexicalTag
NON
ThesaurusID
NLM (2004)
-
Vascular Permeability Factor
Term UI
T087224
Date01/01/1955
LexicalTag
NON
ThesaurusID
NLM (2004)
-
Vasculotropin
Term UI
T207077
Date01/01/1955
LexicalTag
NON
ThesaurusID
NLM (2004)
-
VEGF
Term UI
T087210
Date01/01/1955
LexicalTag
ACR
ThesaurusID
NLM (2004)
-
VEGF-A
Term UI
T406108
Date01/31/2000
LexicalTag
ACR
ThesaurusID
NLM (2004)