MeSH Browser

MeSH Heading: Receptor, TIE-2
Tree Number(s): D08.811.913.696.620.682.725.400.925.500; D12.776.476.568.400.925.500; D12.776.543.750.630.687.500
Unique ID: D042787
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D042787
Annotation: see SCR for organism-specific terms
Scope Note: A TIE receptor tyrosine kinase that is found almost exclusively on ENDOTHELIAL CELLS. It is required for both normal embryonic vascular development (NEOVASCULARIZATION, PHYSIOLOGIC) and tumor angiogenesis (NEOVASCULARIZATION, PATHOLOGIC).
Entry Version: RECEPT TIE 2
Entry Term(s): Angiopoietin Receptor Tie-2; TIE-2 Receptor Tyrosine Kinase; TIE-2-RTK; TIE2 Tyrosine Kinase; Tek Receptor; Tie2 Receptor
Previous Indexing: Protein-Tyrosine Kinase (1993); Receptor Protein-Tyrosine Kinases (1994-2003)
Public MeSH Note: 2004; TIE-2 RECEPTOR TYROSINE KINASE (now RECEPTOR TIE-2) was indexed under RECEPTOR PROTEIN-TYROSINE KINASES 1994-2004 & under PROTEIN-TYROSINE KINASE 1993
History Note: 2004; use RECEPTOR TIE-2 (NM) 1993-2003
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2021/05/21

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0217220
Scope Note: A TIE receptor tyrosine kinase that is found almost exclusively on ENDOTHELIAL CELLS. It is required for both normal embryonic vascular development (NEOVASCULARIZATION, PHYSIOLOGIC) and tumor angiogenesis (NEOVASCULARIZATION, PATHOLOGIC).
Terms: Receptor, TIE-2 Preferred Term
Term UI T526007
Date11/13/2002
LexicalTag ACX
ThesaurusID NLM (2004); TIE2 Tyrosine Kinase
Term UI T247221
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2004); TIE-2 Receptor Tyrosine Kinase
Term UI T247225
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2004); TIE-2-RTK
Term UI T247220
Date01/01/1955
LexicalTag ACR
ThesaurusID NLM (2004); Tie2 Receptor
Term UI T416776
Date06/15/2000
LexicalTag ACX
ThesaurusID NLM (2004); Tek Receptor
Term UI T526008
Date11/13/2002
LexicalTag ACX
ThesaurusID NLM (2004); Angiopoietin Receptor Tie-2
Term UI T402063
Date12/09/1999
LexicalTag ACX
ThesaurusID NLM (2004)

Receptor, TIE-2 MeSH Descriptor Data 2025