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A TIE receptor found predominantly on ENDOTHELIAL CELLS. It is considered essential for vascular development and can form a heterodimer with the TIE-2 RECEPTOR. The TIE-1 receptor may play a role in regulating BLOOD VESSEL stability and maturation.
Entry Version
RECEPT TIE 1
Entry Term(s)
TIE-1 Receptor Tyrosine Kinase
TIE1 Tyrosine Kinase
Registry Numbers
EC 2.7.10.1
Previous Indexing
Protein-Tyrosine Kinase (1992-1993)
Receptor Protein-Tyrosine Kinase (1994-2003)
Receptors, Cell Surface (1994-2003)
Public MeSH Note
2004; TIE-1 RECEPTOR TYROSINE KINASE & TIE1 TYROSINE KINASE were indexed under RECEPTORS, CELL SURFACE & RECEPTOR PROTEIN-TYROSINE KINASES 1993-2003
History Note
2004; for TIE-1 RECEPTOR TYROSINE KINASE & TIE1 TYROSINE KINASE use RECEPTOR, TIE-1 (NM) 1993-2003
A TIE receptor found predominantly on ENDOTHELIAL CELLS. It is considered essential for vascular development and can form a heterodimer with the TIE-2 RECEPTOR. The TIE-1 receptor may play a role in regulating BLOOD VESSEL stability and maturation.