MeSH Browser

MeSH Heading: Carboxylesterase
Tree Number(s): D08.811.277.352.100.100
Unique ID: D043182
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D043182
Scope Note: Carboxylesterase is a serine-dependent esterase with wide substrate specificity. The enzyme is involved in the detoxification of XENOBIOTICS and the activation of ester and of amide PRODRUGS.
Entry Term(s): Ali-esterase; B-esterase; CAP-hydrolyzing Enzyme; Capsaicin-Hydrolyzing Enzyme; Carboxyesterase; Carboxylate Esterase; Carboxylester Lipase; Carboxylesterase B; Carboxylic Ester Hydrolase; Esterase 10; Esterase 13; Esterase 3; Esterase 6A; Esterase 8; Esterase ES-1A; Hydrolase S; Isocarboxazid amidase; Naproxen Esterase; Non-specific Carboxylesterase; Non-specific Esterase; Nonspecific Esterase; Procaine Esterase
Related Numbers: 9016-18-6; EC 3.1.1.1
Previous Indexing: Carboxylic Ester Hydrolases (1981-2003)
Public MeSH Note: 2004; CARBOXYLESTERASE was indexed under CARBOXYLIC ACID ESTERASES 1981-2003
History Note: 2004; use CARBOXYLESTERASE (NM) 1981 - 2003
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 1955/01/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Esterases [D08.811.277.352]
      - Carboxylic Ester Hydrolases [D08.811.277.352.100]
        
        Acetylesterase [D08.811.277.352.100.050]
        
        Carboxylesterase [D08.811.277.352.100.100]
        
        Cholinesterases [D08.811.277.352.100.170]
        
        Dehydroascorbatase [D08.811.277.352.100.220]
        
        Lipase [D08.811.277.352.100.400]
        
        Lipoprotein Lipase [D08.811.277.352.100.430]
        
        Monoacylglycerol Lipases [D08.811.277.352.100.500]
        
        Naphthol AS D Esterase [D08.811.277.352.100.550]
        
        Phospholipases [D08.811.277.352.100.680]
        
        Sterol Esterase [D08.811.277.352.100.700]

Carboxylesterase Preferred

Concept UI: M0090456
Related Numbers: 9016-18-6; EC 3.1.1.1
Scope Note: Carboxylesterase is a serine-dependent esterase with wide substrate specificity. The enzyme is involved in the detoxification of XENOBIOTICS and the activation of ester and of amide PRODRUGS.
Terms: Carboxylesterase Preferred Term
Term UI T120459
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Non-specific Esterase
Term UI T120452
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Nonspecific Esterase
Term UI T120453
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Procaine Esterase
Term UI T120457
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Naproxen Esterase
Term UI T120450
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Ali-esterase
Term UI T120423
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); B-esterase
Term UI T120420
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); CAP-hydrolyzing Enzyme
Term UI T120421
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Capsaicin-Hydrolyzing Enzyme
Term UI T120425
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Carboxyesterase
Term UI T120426
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Carboxylate Esterase
Term UI T120428
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Carboxylester Lipase
Term UI T120427
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Carboxylesterase B
Term UI T120429
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Carboxylic Ester Hydrolase
Term UI T120431
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Non-specific Carboxylesterase
Term UI T120451
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Isocarboxazid amidase
Term UI T120449
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004)

Esterase 13 Narrower

Esterase 3 Narrower

Esterase 6A Narrower

Esterase 8 Narrower

Esterase ES-1A Narrower

Esterase 10 Narrower

Hydrolase S Narrower

Carboxylesterase MeSH Descriptor Data 2025