MeSH Browser

MeSH Heading: Ubiquitin-Activating Enzymes
Tree Number(s): D08.811.464.938.249
Unique ID: D044764
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D044764
Scope Note: A class of enzymes that catalyzes the ATP-dependent formation of a thioester bond between itself and UBIQUITIN. It then transfers the activated ubiquitin to one of the UBIQUITIN-PROTEIN LIGASES.
Entry Term(s): Ubiquitin-Activating Enzyme; Ubiquitin-Activating Enzyme E1; Ubiquitination Activating Enzyme E1
Previous Indexing: Ligases (1983-2003)
Public MeSH Note: 2004; UBIQUITIN-ACTIVATING ENZYME was indexed under LIGASES 1983-2003
History Note: 2004; use UBIQUITIN-ACTIVATING ENZYMES (NM) 1983-2003
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2016/06/02

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0446165
Scope Note: A class of enzymes that catalyzes the ATP-dependent formation of a thioester bond between itself and UBIQUITIN. It then transfers the activated ubiquitin to one of the UBIQUITIN-PROTEIN LIGASES.
Terms: Ubiquitin-Activating Enzymes Preferred Term
Term UI T533920
Date02/27/2003
LexicalTag NON
ThesaurusID NLM (2004); Ubiquitin-Activating Enzyme
Term UI T145795
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Ubiquitin-Activating Enzyme E1
Term UI T145796
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Ubiquitination Activating Enzyme E1
Term UI T145799
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004)

Ubiquitin-Activating Enzymes MeSH Descriptor Data 2025