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beta-Mannosidase MeSH Descriptor Data 2022


MeSH Heading
beta-Mannosidase
Tree Number(s)
D08.811.277.450.625.750
Unique ID
D044902
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D044902
Annotation
/defic: consider also BETA-MANNOSIDOSIS
Scope Note
An enzyme that catalyzes the hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides. The enzyme plays a role in the lysosomal degradation of the N-glycosylprotein glycans. Defects in the lysosomal form of the enzyme in humans result in a buildup of mannoside intermediate metabolites and the disease BETA-MANNOSIDOSIS.
Entry Term(s)
beta-D-Mannosidase
beta-Mannanase
manA protein (beta-Mannosidase)
Registry Number
EC 3.2.1.25
Related Numbers
9025-43-8
Previous Indexing
Mannosidases (1980-2003)
See Also
beta-Mannosidosis
Public MeSH Note
2004; BETA-MANNOSIDASE was indexed under MANNOSIDASES 1980-2003
History Note
2004; use BETA-MANNOSIDASE (NM) 1980-2003
Date Established
2004/01/01
Date of Entry
2003/07/09
beta-Mannosidase Preferred
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