MeSH Browser

MeSH Heading: Nesidioblastosis
Tree Number(s): C06.689.150.500; C16.614.200.500; C18.452.394.968.250.500; C18.452.394.984.200.500
Unique ID: D046768
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D046768
Scope Note: An inherited autosomal recessive syndrome characterized by the disorganized formation of new islets in the PANCREAS and CONGENITAL HYPERINSULINISM. It is due to focal hyperplasia of pancreatic ISLET CELLS budding off from the ductal structures and forming new islets of Langerhans. Mutations in the islet cells involve the potassium channel gene KCNJ11 or the ATP-binding cassette transporter gene ABCC8, both on CHROMOSOME 11.
Entry Term(s): Hyperinsulinism, Familial, with Pancreatic Nesidioblastosis; Nesidioblastosis of Pancreas; Pancreatic Nesidioblastosis
Previous Indexing: Hyperinsulinism (1971-2004); Hyperplasia (1968-2004); Islets of Langerhans (1968-2004)
See Also: ATP-Binding Cassette Transporters; KATP Channels
Public MeSH Note: 2005; see PANCREATIC DISEASES 1983-2004
History Note: 2005; use PANCREATIC DISEASES 1983-2004
Date Established: 2005/01/01
Date of Entry: 2004/07/07
Revision Date: 2012/07/03

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Concept UI: M0015793
Scope Note: An inherited autosomal recessive syndrome characterized by the disorganized formation of new islets in the PANCREAS and CONGENITAL HYPERINSULINISM. It is due to focal hyperplasia of pancreatic ISLET CELLS budding off from the ductal structures and forming new islets of Langerhans. Mutations in the islet cells involve the potassium channel gene KCNJ11 or the ATP-binding cassette transporter gene ABCC8, both on CHROMOSOME 11.
Terms: Nesidioblastosis Preferred Term
Term UI T030136
Date04/26/1982
LexicalTag NON
ThesaurusID; Hyperinsulinism, Familial, with Pancreatic Nesidioblastosis
Term UI T555625
Date10/30/2003
LexicalTag NON
ThesaurusID; Nesidioblastosis of Pancreas
Term UI T555624
Date10/30/2003
LexicalTag NON
ThesaurusID; Pancreatic Nesidioblastosis
Term UI T555627
Date10/30/2003
LexicalTag NON
ThesaurusID NLM (2005)

Nesidioblastosis MeSH Descriptor Data 2025