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Nesidioblastosis MeSH Descriptor Data 2023


MeSH Heading
Nesidioblastosis
Tree Number(s)
C06.689.150.500
C16.614.200.500
C18.452.394.968.250.500
C18.452.394.984.200.500
Unique ID
D046768
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D046768
Scope Note
An inherited autosomal recessive syndrome characterized by the disorganized formation of new islets in the PANCREAS and CONGENITAL HYPERINSULINISM. It is due to focal hyperplasia of pancreatic ISLET CELLS budding off from the ductal structures and forming new islets of Langerhans. Mutations in the islet cells involve the potassium channel gene KCNJ11 or the ATP-binding cassette transporter gene ABCC8, both on CHROMOSOME 11.
Entry Term(s)
Hyperinsulinism, Familial, with Pancreatic Nesidioblastosis
Nesidioblastosis of Pancreas
Pancreatic Nesidioblastosis
Previous Indexing
Hyperinsulinism (1971-2004)
Hyperplasia (1968-2004)
Islets of Langerhans (1968-2004)
See Also
ATP-Binding Cassette Transporters
KATP Channels
Public MeSH Note
2005; see PANCREATIC DISEASES 1983-2004
History Note
2005; use PANCREATIC DISEASES 1983-2004
Date Established
2005/01/01
Date of Entry
2004/07/07
Revision Date
2012/07/03
Nesidioblastosis Preferred
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