MeSH Browser

MeSH Heading: PPAR alpha
Tree Number(s): D12.776.826.239.500
Unique ID: D047493
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D047493
Scope Note: A nuclear transcription factor. Heterodimerization with RETINOID X RECEPTOR GAMMA is important to metabolism of LIPIDS. It is the target of FIBRATES to control HYPERLIPIDEMIAS.
Entry Term(s): PPARalpha; Peroxisome Proliferator-Activated Receptor alpha
Registry Numbers: 0
Previous Indexing: Transcription Factors (1993-2004)
Public MeSH Note: 2005; PPAR ALPHA was indexed under TRANSCRIPTION FACTORS & RECEPTORS, CYTOPLASMIC AND NUCLEAR 1994-2004, and under RECEPTORS, ENDOGENOUS SUBSTANCES 1992-1993
History Note: 2005(1992)
Date Established: 2005/01/01
Date of Entry: 2004/07/07
Revision Date: 2015/06/23

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

PPAR alpha MeSH Descriptor Data 2025