MeSH Browser

MeSH Heading: p38 Mitogen-Activated Protein Kinases
Tree Number(s): D08.811.913.696.620.682.700.567.843; D12.776.476.563.567.843
Unique ID: D048051
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D048051
Scope Note: A mitogen-activated protein kinase subfamily that regulates a variety of cellular processes including CELL GROWTH PROCESSES; CELL DIFFERENTIATION; APOPTOSIS; and cellular responses to INFLAMMATION. The P38 MAP kinases are regulated by CYTOKINE RECEPTORS and can be activated in response to bacterial pathogens.
Entry Term(s): Mitogen-Activated Protein Kinase p38; p38 MAP Kinase; p38 MAPK; p38 Mitogen-Activated Protein Kinase; p38 Protein Kinase; p38 SAPK
Previous Indexing: Ca(2+)-Calmodulin Dependent Protein Kinase (1994-2000); Mitogen-Activated Protein Kinases (2000-2004)
Public MeSH Note: 2005; P38 MITOGEN-ACTIVATED PROTEIN KINASES was indexed under MITOGEN-ACTIVATED PROTEIN KINASES 2001-2004 & under CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE 1994-2000
History Note: 2005(1994)
Date Established: 2005/01/01
Date of Entry: 2004/07/08
Revision Date: 2021/05/21

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0234432
Scope Note: A mitogen-activated protein kinase subfamily that regulates a variety of cellular processes including CELL GROWTH PROCESSES; CELL DIFFERENTIATION; APOPTOSIS; and cellular responses to INFLAMMATION. The P38 MAP kinases are regulated by CYTOKINE RECEPTORS and can be activated in response to bacterial pathogens.
Terms: p38 Mitogen-Activated Protein Kinases Preferred Term
Term UI T572018
Date02/09/2004
LexicalTag NON
ThesaurusID NLM (2005); Mitogen-Activated Protein Kinase p38
Term UI T264437
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2005); p38 MAP Kinase
Term UI T414320
Date05/15/2000
LexicalTag ACX
ThesaurusID NLM (2005); p38 Mitogen-Activated Protein Kinase
Term UI T001003236
Date12/19/2019
LexicalTag NON
ThesaurusID NLM (2021); p38 MAPK
Term UI T433930
Date01/23/2001
LexicalTag ACX
ThesaurusID NLM (2005); p38 SAPK
Term UI T489459
Date04/13/2002
LexicalTag ACX
ThesaurusID NLM (2005); p38 Protein Kinase
Term UI T414321
Date05/15/2000
LexicalTag NON
ThesaurusID NLM (2005)

p38 Mitogen-Activated Protein Kinases MeSH Descriptor Data 2025