MeSH Browser

MeSH Heading: Mitogen-Activated Protein Kinase 6
Tree Number(s): D08.811.913.696.620.682.700.567.249.875; D12.776.476.563.567.249.875
Unique ID: D048053
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D048053
Scope Note: A 97-kDa extracellular signal-regulated MAP kinase. Mitogen-activated protein kinase 6 levels increase during cellular differentiation, while in proliferating cells the enzyme is degraded rapidly via the PROTEASOME ENDOPEPTIDASE COMPLEX.
Entry Term(s): ERK3 Kinase; Extracellular Signal-Regulated Kinase 3; MAPK6 Mitogen-Activated Protein Kinase; p97(MAPK) Protein; p97MAPK Protein
Previous Indexing: Mitogen-Activated Protein Kinases (1991-2004)
Public MeSH Note: 2005; MITOGEN-ACTIVATED PROTEIN KINASE 6 was indexed under MITOGEN-ACTIVATED PROTEIN KINASES 2000-2004, under CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE 1994-2000 & under PROTEIN KINASES 1991-1993
History Note: 2005(1991)
Date Established: 2005/01/01
Date of Entry: 2004/07/07
Revision Date: 2021/05/21

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0188319
Scope Note: A 97-kDa extracellular signal-regulated MAP kinase. Mitogen-activated protein kinase 6 levels increase during cellular differentiation, while in proliferating cells the enzyme is degraded rapidly via the PROTEASOME ENDOPEPTIDASE COMPLEX.
Terms: Mitogen-Activated Protein Kinase 6 Preferred Term
Term UI T571703
Date02/06/2004
LexicalTag NON
ThesaurusID NLM (2005); Extracellular Signal-Regulated Kinase 3
Term UI T218324
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2005); p97MAPK Protein
Term UI T414666
Date05/18/2000
LexicalTag ACX
ThesaurusID NLM (2005); p97(MAPK) Protein
Term UI T414667
Date05/18/2000
LexicalTag ACX
ThesaurusID NLM (2005); ERK3 Kinase
Term UI T572026
Date02/09/2004
LexicalTag ACX
ThesaurusID NLM (2005); MAPK6 Mitogen-Activated Protein Kinase
Term UI T574111
Date02/24/2004
LexicalTag ACX
ThesaurusID NLM (2005)

Mitogen-Activated Protein Kinase 6 MeSH Descriptor Data 2025