MeSH Browser

MeSH Heading: MAP Kinase Kinase 1
Tree Number(s): D08.811.913.696.620.682.700.565.100; D08.811.913.696.620.682.725.200.100; D12.776.476.563.565.100; D12.776.476.568.200.100
Unique ID: D048369
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D048369
Scope Note: An abundant 43-kDa mitogen-activated protein kinase kinase subtype with specificity for MITOGEN-ACTIVATED PROTEIN KINASE 1 and MITOGEN-ACTIVATED PROTEIN KINASE 3.
Entry Term(s): MAP2K1 Protein; MAPK Kinase 1; MEK-1 Protein Kinase; MEK1 Protein Kinase; MKK-1 Protein Kinase; MKK1 Protein Kinase; Mitogen-Activated Protein Kinase Kinase 1
Registry Numbers: EC 2.7.12.2
Previous Indexing: Mitogen-Activated Protein Kinase Kinases (2000-2004); Protein-Serine-Threonine Kinases (1992-2004); Protein-Tyrosine Kinase (1992-1999)
Public MeSH Note: 2005; MAP KINASE KINASE 1 was indexed under MITOGEN-ACTIVATED PROTEIN KINASE KINASES 2000-2004, under PROTEIN-SERINE-THREONINE KINASES 1992-2004 & under PROTEIN-TYROSINE KINASE 1992-1999
History Note: 2005(1999)
Date Established: 2005/01/01
Date of Entry: 2004/07/07
Revision Date: 2021/05/21

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0208001
Registry Numbers: EC 2.7.12.2
Scope Note: An abundant 43-kDa mitogen-activated protein kinase kinase subtype with specificity for MITOGEN-ACTIVATED PROTEIN KINASE 1 and MITOGEN-ACTIVATED PROTEIN KINASE 3.
Terms: MAP Kinase Kinase 1 Preferred Term
Term UI T238005
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2005); MKK1 Protein Kinase
Term UI T576022
Date03/09/2004
LexicalTag ACX
ThesaurusID NLM (2005); MEK1 Protein Kinase
Term UI T576023
Date03/09/2004
LexicalTag ACX
ThesaurusID NLM (2005); Mitogen-Activated Protein Kinase Kinase 1
Term UI T576516
Date03/11/2004
LexicalTag NON
ThesaurusID NLM (2005); MKK-1 Protein Kinase
Term UI T581311
Date04/06/2004
LexicalTag ACX
ThesaurusID NLM (2005); MEK-1 Protein Kinase
Term UI T581312
Date04/06/2004
LexicalTag ACX
ThesaurusID NLM (2005); MAPK Kinase 1
Term UI T238003
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2005); MAP2K1 Protein
Term UI T581313
Date04/06/2004
LexicalTag ACX
ThesaurusID NLM (2005)

MAP Kinase Kinase 1 MeSH Descriptor Data 2025