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Succinate-Semialdehyde Dehydrogenase MeSH Descriptor Data 2022


MeSH Heading
Succinate-Semialdehyde Dehydrogenase
Tree Number(s)
D08.811.682.657.163.843
Unique ID
D050644
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D050644
Scope Note
An enzyme that plays a role in the GLUTAMATE and butanoate metabolism pathways by catalyzing the oxidation of succinate semialdehyde to SUCCINATE using NAD+ as a coenzyme. Deficiency of this enzyme, causes 4-hydroxybutyricaciduria, a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA).
Entry Term(s)
NAD(+)-Dependent Succinic Semialdehyde Dehydrogenase
Succinate Semialdehyde Dehydrogenase
Succinic Semialdehyde Dehydrogenase
Registry Number
EC 1.2.1.24
Related Numbers
9028-95-9
Public MeSH Note
2006; SUCCINATE-SEMIALDEHYDE DEHYDROGENASE was indexed under ALDEHYDE OXIDOREDUCTASES 1977-2005
History Note
2006(1980); use ALDEHYDE OXIDREDUCTASES 1977-1979
Date Established
2006/01/01
Date of Entry
2005/06/30
Succinate-Semialdehyde Dehydrogenase Preferred
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