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2-Oxoisovalerate Dehydrogenase (Acylating) MeSH Descriptor Data 2026
An NAD+ dependent enzyme that catalyzes the oxidation 3-methyl-2-oxobutanoate to 2-methylpropanoyl-CoA. It plays a role in the degradation of VALINE; LEUCINE; and ISOLEUCINE.
Entry Term(s)
2-Oxoisovalerate Dehydrogenase
alpha-Ketoisovalerate Dehydrogenase
Registry Numbers
EC 1.2.1.25
Related Numbers
37211-61-3
Public MeSH Note
2006; 2-OXOISOVALERATE DEHYDROGENASE (ACYLATING) was indexed under KETONE OXIDOREDUCTASES 1983-2005, under AMINO ACIDS, BRANCHED-CHAIN 1979-1982, under KETO ACIDS 1973-1982, & VALERATES 1973-1979
An NAD+ dependent enzyme that catalyzes the oxidation 3-methyl-2-oxobutanoate to 2-methylpropanoyl-CoA. It plays a role in the degradation of VALINE; LEUCINE; and ISOLEUCINE.