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2-Oxoisovalerate Dehydrogenase (Acylating) MeSH Descriptor Data 2026


MeSH Heading
2-Oxoisovalerate Dehydrogenase (Acylating)
Tree Number(s)
D08.811.682.657.350.825
Unique ID
D050645
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D050645
Scope Note
An NAD+ dependent enzyme that catalyzes the oxidation 3-methyl-2-oxobutanoate to 2-methylpropanoyl-CoA. It plays a role in the degradation of VALINE; LEUCINE; and ISOLEUCINE.
Entry Term(s)
2-Oxoisovalerate Dehydrogenase
alpha-Ketoisovalerate Dehydrogenase
Registry Numbers
EC 1.2.1.25
Related Numbers
37211-61-3
Public MeSH Note
2006; 2-OXOISOVALERATE DEHYDROGENASE (ACYLATING) was indexed under KETONE OXIDOREDUCTASES 1983-2005, under AMINO ACIDS, BRANCHED-CHAIN 1979-1982, under KETO ACIDS 1973-1982, & VALERATES 1973-1979
History Note
2006(1980); use AMINO ACIDS, BRANCHED-CHAIN 1979, & KETO ACIDS & VALERATES 1973-1979
Date Introduced
2006/01/01
Last Updated
2006/01/01
2-Oxoisovalerate Dehydrogenase (Acylating) Preferred
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