MeSH Browser

MeSH Heading: Synaptotagmin I
Tree Number(s): D12.776.157.125.825.249; D12.776.543.990.850.249
Unique ID: D050863
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D050863
Scope Note: A vesicular transport protein expressed predominately in NEURONS. Synaptotagmin helps regulate EXOCYTOSIS of SYNAPTIC VESICLES and appears to serve as a calcium sensor to trigger NEUROTRANSMITTER release. It also acts as a nerve cell receptor for certain BOTULINUM TOXINS.
Entry Term(s): Synaptic Vesicle Protein p65; Synaptotagmin 1; p65 Protein (Synaptotagmin I)
Registry Numbers: 0
Public MeSH Note: 2006; SYNAPTOTAGMIN I was indexed under CALCIUM-BINDING PROTEINS, MEMRANE GLYCOPROTEINS, & NERVE TISSUE PROTEINS 1991-2005
History Note: 2006(1991)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2010/06/25

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0183221
Registry Numbers: 0
Scope Note: A vesicular transport protein expressed predominately in NEURONS. Synaptotagmin helps regulate EXOCYTOSIS of SYNAPTIC VESICLES and appears to serve as a calcium sensor to trigger NEUROTRANSMITTER release. It also acts as a nerve cell receptor for certain BOTULINUM TOXINS.
Terms: Synaptotagmin I Preferred Term
Term UI T213226
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); Synaptic Vesicle Protein p65
Term UI T213225
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); Synaptotagmin 1
Term UI T625464
Date12/22/2004
LexicalTag NON
ThesaurusID NLM (2006); p65 Protein (Synaptotagmin I)
Term UI T764457
Date01/20/2010
LexicalTag NON
ThesaurusID NLM (2011)

Synaptotagmin I MeSH Descriptor Data 2024