MeSH Browser

MeSH Heading: Glial Cell Line-Derived Neurotrophic Factor
Tree Number(s): D12.644.276.860.381.500; D12.776.467.860.381.500; D12.776.631.600.381.500; D23.529.850.381.500
Unique ID: D051100
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051100
Annotation: GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTORS is also available
Scope Note: The founding member of the glial cell line-derived neurotrophic factor family. It was originally characterized as a NERVE GROWTH FACTOR promoting the survival of MIDBRAIN dopaminergic NEURONS, and it has been studied as a potential treatment for PARKINSON DISEASE.
Entry Term(s): GDNF; GDNF Growth Factor; Glial Cell-Derived Neurotrophic Factor; Glial Cell-Line Derived Neurotrophic Factor; Glial-Derived Neurotrophic Factor
Public MeSH Note: 2006; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR was indexed under NERVE GROWTH FACTORS 2003-2005, & under NERVE TISSUE PROTEINS 1993-2002
History Note: 2006(1993)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2020/01/16

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0233028
Scope Note: The founding member of the glial cell line-derived neurotrophic factor family. It was originally characterized as a NERVE GROWTH FACTOR promoting the survival of MIDBRAIN dopaminergic NEURONS, and it has been studied as a potential treatment for PARKINSON DISEASE.
Terms: Glial Cell Line-Derived Neurotrophic Factor Preferred Term
Term UI T633304
Date03/14/2005
LexicalTag NON
ThesaurusID NLM (2006); GDNF
Term UI T263032
Date01/01/1955
LexicalTag ACR
ThesaurusID NLM (2006); Glial Cell-Line Derived Neurotrophic Factor
Term UI T263033
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); Glial Cell-Derived Neurotrophic Factor
Term UI T000999260
Date11/22/2019
LexicalTag NON
ThesaurusID NLM (2021); Glial-Derived Neurotrophic Factor
Term UI T000999261
Date11/22/2019
LexicalTag NON
ThesaurusID NLM (2021); GDNF Growth Factor
Term UI T633305
Date03/14/2005
LexicalTag ABX
ThesaurusID NLM (2006)

Glial Cell Line-Derived Neurotrophic Factor MeSH Descriptor Data 2025