MeSH Browser

MeSH Heading: ZAP-70 Protein-Tyrosine Kinase
Tree Number(s): D08.811.913.696.620.682.725.900; D12.776.476.568.900
Unique ID: D051746
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051746
Scope Note: A protein tyrosine kinase that is required for T-CELL development and T-CELL ANTIGEN RECEPTOR function.
Entry Term(s): 70 kDa Zeta-Associated Protein; Syk-Related Tyrosine Kinase; ZAP-70 Kinase; ZAP-70 Protein; zeta-Chain Associated Protein Kinase (ZAP-70)
See Also: src Homology Domains
Public MeSH Note: 2006; ZAP-70 KINASE was indexed under PROTEIN-TYROSINE KINASE 1992-2005
History Note: 2006(1992)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2021/05/21

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0209216
Scope Note: A protein tyrosine kinase that is required for T-CELL development and T-CELL ANTIGEN RECEPTOR function.
Terms: ZAP-70 Protein-Tyrosine Kinase Preferred Term
Term UI T638352
Date04/28/2005
LexicalTag NON
ThesaurusID NLM (2006); ZAP-70 Protein
Term UI T239219
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2006); ZAP-70 Kinase
Term UI T239221
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); Syk-Related Tyrosine Kinase
Term UI T614331
Date10/19/2004
LexicalTag ABX
ThesaurusID NLM (2006); 70 kDa Zeta-Associated Protein
Term UI T614332
Date10/19/2004
LexicalTag ABX
ThesaurusID NLM (2006); zeta-Chain Associated Protein Kinase (ZAP-70)
Term UI T747849
Date03/19/2009
LexicalTag ABX
ThesaurusID NLM (2010)

ZAP-70 Protein-Tyrosine Kinase MeSH Descriptor Data 2025