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Smad6 Protein
MeSH Descriptor Data 2025
Details
Qualifiers
MeSH Tree Structures
Concepts
MeSH Heading
Smad6 Protein
Tree Number(s)
D12.644.360.024.334.200.600
D12.776.157.057.170.249.600
D12.776.476.024.428.249.600
D12.776.930.806.875
Unique ID
D051905
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D051905
Scope Note
An inhibitory Smad protein that negatively regulates the
SIGNAL TRANSDUCTION PATHWAYS
from
BONE MORPHOGENETIC PROTEIN RECEPTORS
. Smad6 inhibits
PHOSPHORYLATION
of
SMAD2 PROTEIN
and
SMAD3 PROTEIN
.
Public MeSH Note
2006; SMAD6 PROTEIN was indexed under DNA-BINDING PROTEINS & TRANS-ACTIVATORS 1997-2005
History Note
2006(1997)
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2016/02/18
Allowable Qualifiers
administration & dosage (AD)
adverse effects (AE)
agonists (AG)
analysis (AN)
antagonists & inhibitors (AI)
biosynthesis (BI)
blood (BL)
cerebrospinal fluid (CF)
chemical synthesis (CS)
chemistry (CH)
classification (CL)
deficiency (DF)
drug effects (DE)
economics (EC)
genetics (GE)
history (HI)
immunology (IM)
isolation & purification (IP)
metabolism (ME)
pharmacokinetics (PK)
pharmacology (PD)
physiology (PH)
poisoning (PO)
radiation effects (RE)
standards (ST)
supply & distribution (SD)
therapeutic use (TU)
toxicity (TO)
ultrastructure (UL)
urine (UR)
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Adaptor Proteins, Signal Transducing [D12.644.360.024]
Smad Proteins [D12.644.360.024.334]
Smad Proteins, Inhibitory [D12.644.360.024.334.200]
Smad6 Protein [D12.644.360.024.334.200.600]
Smad7 Protein [D12.644.360.024.334.200.700]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Adaptor Proteins, Signal Transducing [D12.776.157.057]
Smad Proteins [D12.776.157.057.170]
Smad Proteins, Inhibitory [D12.776.157.057.170.249]
Smad6 Protein [D12.776.157.057.170.249.600]
Smad7 Protein [D12.776.157.057.170.249.700]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Adaptor Proteins, Signal Transducing [D12.776.476.024]
Smad Proteins [D12.776.476.024.428]
Smad Proteins, Inhibitory [D12.776.476.024.428.249]
Smad6 Protein [D12.776.476.024.428.249.600]
Smad7 Protein [D12.776.476.024.428.249.700]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Transcription Factors [D12.776.930]
Smad Proteins [D12.776.930.806]
Smad Proteins, Receptor-Regulated [D12.776.930.806.500]
Smad4 Protein [D12.776.930.806.750]
Smad6 Protein [D12.776.930.806.875]
Expand All
Collapse All
Smad6 Protein
Preferred
Concept UI
M0278165
Scope Note
An inhibitory Smad protein that negatively regulates the
SIGNAL TRANSDUCTION PATHWAYS
from
BONE MORPHOGENETIC PROTEIN RECEPTORS
. Smad6 inhibits
PHOSPHORYLATION
of
SMAD2 PROTEIN
and
SMAD3 PROTEIN
.
Terms
Smad6 Protein
Preferred Term
Term UI
T308170
Date
01/01/1955
LexicalTag
NON
ThesaurusID
NLM (2006)
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