MeSH Browser

MeSH Heading: Apoprotein(a)
Tree Number(s): D10.532.350.500; D12.776.521.400.500
Unique ID: D053241
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D053241
Annotation: do not confuse with APOLIPOPROTEINS A, normal structural proteins of the alpha-lipoproteins (HIGH DENSITY LIPOPROTEINS)
Scope Note: A large and highly glycosylated protein constituent of LIPOPROTEIN (A). It has very little affinity for lipids but forms disulfide-linkage to APOLIPOPROTEIN B-100. Apoprotein(a) has SERINE PROTEINASE activity and can be of varying sizes from 400- to 800-kDa. It is homologous to PLASMINOGEN and is known to modulate THROMBOSIS and FIBRINOLYSIS.
Entry Term(s): Antiangiogenic AK38 Protein; Apo Lp(a); Apolipoprotein (a); Apolipoprotein Lp(a); Apolipoprotein Lp(a+); Apolipoprotein(a); Apoprotein (a)
Registry Numbers: EC 3.4.21.-
Previous Indexing: Apolipoproteins (1977-1993); Apolipoproteins A (1982-2006); Apoproteins (1978-2004)
Public MeSH Note: 2007; see APOLIPOPROTEINS A 1988-2006; APOLIPOPROTEIN LP(A+) was indexed under APOLIPOPROTEINS & LIPOPROTEIN(A) 1986-2006
History Note: 2007 (1986); use APOLIPOPROTEINS A 1988-2006
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2009/07/20

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0001595
Registry Numbers: EC 3.4.21.-
Scope Note: A large and highly glycosylated protein constituent of LIPOPROTEIN (A). It has very little affinity for lipids but forms disulfide-linkage to APOLIPOPROTEIN B-100. Apoprotein(a) has SERINE PROTEINASE activity and can be of varying sizes from 400- to 800-kDa. It is homologous to PLASMINOGEN and is known to modulate THROMBOSIS and FIBRINOLYSIS.
Terms: Apoprotein(a) Preferred Term
Term UI T660265
Date11/29/2005
LexicalTag ABB
ThesaurusID NLM (2007); Apolipoprotein(a)
Term UI T406740
Date02/09/2000
LexicalTag NON
ThesaurusID NLM (2007); Apoprotein (a)
Term UI T003204
Date08/08/1988
LexicalTag NON
ThesaurusID UNK (19XX); Antiangiogenic AK38 Protein
Term UI T660281
Date11/29/2005
LexicalTag NON
ThesaurusID NLM (2007); Apolipoprotein Lp(a+)
Term UI T173153
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2007); Apolipoprotein (a)
Term UI T173152
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2007); Apolipoprotein Lp(a)
Term UI T660280
Date11/29/2005
LexicalTag ABX
ThesaurusID NLM (2007); Apo Lp(a)
Term UI T173151
Date01/01/1955
LexicalTag ABB
ThesaurusID NLM (2007)

Apoprotein(a) MeSH Descriptor Data 2025