MeSH Browser

MeSH Heading: Interleukin-1alpha
Tree Number(s): D12.644.276.374.465.010.300; D12.644.276.374.500.400.300; D12.776.467.374.465.010.300; D12.776.467.374.500.400.300; D23.529.374.465.131.300; D23.529.374.500.400.300
Unique ID: D053582
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D053582
Scope Note: An interleukin-1 subtype that occurs as a membrane-bound pro-protein form that is cleaved by proteases to form a secreted mature form. Unlike INTERLEUKIN-1BETA both membrane-bound and secreted forms of interleukin-1alpha are biologically active.
Entry Version: IL 1ALPHA
Entry Term(s): Hematopoietin-1; IL-1 alpha; Interleukin-1 alpha
Registry Numbers: 0
Previous Indexing: Interleukin-1 (1988-2006)
Public MeSH Note: 2007; see INTERLEUKIN-1 1988-2006; for HEMATOPOIETIN-1 see HEMATOPOIETIC CELL GROWTH FACTORS 1990-2006
History Note: 2007(1988)
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2015/04/15

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0011501
Registry Numbers: 0
Scope Note: An interleukin-1 subtype that occurs as a membrane-bound pro-protein form that is cleaved by proteases to form a secreted mature form. Unlike INTERLEUKIN-1BETA both membrane-bound and secreted forms of interleukin-1alpha are biologically active.
Terms: Interleukin-1alpha Preferred Term
Term UI T022100
Date08/10/1987
LexicalTag NON
ThesaurusID UNK (19XX); Hematopoietin-1
Term UI T048598
Date04/13/1990
LexicalTag NON
ThesaurusID NLM (1991); IL-1 alpha
Term UI T022112
Date10/30/1997
LexicalTag NON
ThesaurusID NLM (1999); Interleukin-1 alpha
Term UI T022101
Date01/15/1991
LexicalTag NON
ThesaurusID NLM (1992)

Interleukin-1alpha MeSH Descriptor Data 2024