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TYK2 Kinase MeSH Descriptor Data 2022


MeSH Heading
TYK2 Kinase
Tree Number(s)
D08.811.913.696.620.682.725.124.650
D12.776.476.568.124.650
Unique ID
D053634
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D053634
Scope Note
A Janus kinase subtype that is involved in signaling from a broad variety of CYTOKINE RECEPTORS. The TYK2 kinase is considered the founding member of the janus kinase family and was initially discovered as a signaling partner for the INTERFERON ALPHA-BETA RECEPTOR. The kinase has since been shown to signal from several INTERLEUKIN RECEPTORS.
Entry Term(s)
Non-Receptor Tyrosine-Protein Kinase TYK2
Tyrosine Kinase 2
Registry Number
EC 2.7.10.2
Previous Indexing
Protein-Tyrosine Kinase (1991-2006)
See Also
src Homology Domains
Public MeSH Note
2007
History Note
2007
Date Established
2007/01/01
Date of Entry
2006/07/05
Revision Date
2021/05/21
TYK2 Kinase Preferred
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