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Scleromyxedema MeSH Descriptor Data 2025


MeSH Heading
Scleromyxedema
Tree Number(s)
C17.300.550.875
Unique ID
D053718
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D053718
Scope Note
A connective tissue disorder characterized by widespread thickening of SKIN with a cobblestone-like appearance. It is caused by proliferation of FIBROBLASTS and deposition of MUCIN in the DERMIS in the absence of thyroid disease. Most scleromyxedema cases are associated with a MONOCLONAL GAMMOPATHY, immunoglobulin IgG-lambda.
Entry Term(s)
Lichen Myxedematosus
Papular Mucinosis
Previous Indexing
Myxedema (1963-2006)
See Also
Myxedema
Public MeSH Note
2007
History Note
2007
Date Established
2007/01/01
Date of Entry
2024/08/09
Revision Date
2024/03/27
Scleromyxedema Preferred
Lichen Myxedematosus Related
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