MeSH Browser

MeSH Heading: Topoisomerase II Inhibitors
Tree Number(s): D27.505.519.389.892.750; D27.505.954.248.794.750
Unique ID: D059005
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D059005
Scope Note: Compounds that inhibit the activity of DNA TOPOISOMERASE II. Included in this category are a variety of ANTINEOPLASTIC AGENTS which target the eukaryotic form of topoisomerase II and ANTIBACTERIAL AGENTS which target the prokaryotic form of topoisomerase II.
Entry Term(s): DNA Gyrase Inhibitor; DNA Gyrase Inhibitors; DNA Topoisomerase II Inhibitor; DNA Topoisomerase II Inhibitors; DNA Type 2 Topoisomerase Inhibitors; Topoisomerase 2 Inhibitors; Topoisomerase II Inhibitor
Registry Number: 0
Previous Indexing: DNA Gyrase/antagonists & inhibitors (1994-2002); DNA Topoisomerases, Type II/antagonists & inhibitors (1994-2010)
Public MeSH Note: 2011
History Note: 2011
Date Established: 2011/01/01
Date of Entry: 2010/06/25
Revision Date: 2020/06/29

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0545767
Registry Number: 0
Scope Note: Compounds that inhibit the activity of DNA TOPOISOMERASE II. Included in this category are a variety of ANTINEOPLASTIC AGENTS which target the eukaryotic form of topoisomerase II and ANTIBACTERIAL AGENTS which target the prokaryotic form of topoisomerase II.
Terms: Topoisomerase II Inhibitors Preferred Term
Term UI T769966
Date04/21/2010
LexicalTag NON
ThesaurusID NLM (2011); DNA Topoisomerase II Inhibitor
Term UI T001083686
Date06/29/2020
LexicalTag NON
ThesaurusID NLM (2021); Topoisomerase 2 Inhibitors
Term UI T769949
Date04/21/2010
LexicalTag NON
ThesaurusID NLM (2011); Topoisomerase II Inhibitor
Term UI T001083684
Date06/29/2020
LexicalTag NON
ThesaurusID NLM (2021); DNA Topoisomerase II Inhibitors
Term UI T769950
Date04/21/2010
LexicalTag ABX
ThesaurusID NLM (2011); DNA Type 2 Topoisomerase Inhibitors
Term UI T769951
Date04/21/2010
LexicalTag ABX
ThesaurusID NLM (2011)

Topoisomerase II Inhibitors MeSH Descriptor Data 2023