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Lopinavir MeSH Descriptor Data 2022


MeSH Heading
Lopinavir
Tree Number(s)
D03.383.742.698.553
Unique ID
D061466
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D061466
Scope Note
An HIV protease inhibitor used in a fixed-dose combination with RITONAVIR. It is also an inhibitor of CYTOCHROME P-450 CYP3A.
Entry Term(s)
A-157378.0
ABT 378
ABT-378
N-(4-(((2,6-dimethylphenoxy)acetyl)amino)-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl)tetrahydro-alpha-(1-methylethyl)-2-oxo-1(2H)-pydrimidineacetamide
Pharm Action
HIV Protease Inhibitors
Cytochrome P-450 CYP3A Inhibitors
Registry Number
2494G1JF75
Public MeSH Note
2012; LOPNAVIR was indexed under PYRIMIDINONES 2000-2011
History Note
2012
Date Established
2012/01/01
Date of Entry
2011/06/27
Revision Date
2016/07/01
Lopinavir Preferred
A-157378.0 Narrower
ABT 378 Narrower
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