MeSH Browser

MeSH Heading: Myeloid Cell Leukemia Sequence 1 Protein
Tree Number(s): D12.644.360.075.718.984; D12.776.476.075.718.968; D12.776.624.664.700.169.500
Unique ID: D064549
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D064549
Scope Note: A member of the myeloid leukemia factor (MLF) protein family with multiple alternatively spliced transcript variants encoding different protein isoforms. In hematopoietic cells, it is located mainly in the nucleus, and in non-hematopoietic cells, primarily in the cytoplasm with a punctate nuclear localization. MLF1 plays a role in cell cycle differentiation.
Entry Term(s): Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1; Myeloid Cell Factor-1; Myeloid Cell Leukemia Sequence 1
Public MeSH Note: 2014; was indexed under NEOPLASM PROTEINS 1993-2008, and PROTO-ONCOGENE PROTEINS C-BCL-2 2009-2013
History Note: 2014
Date Established: 2014/01/01
Date of Entry: 2013/07/08
Revision Date: 2015/11/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0215606
Scope Note: A member of the myeloid leukemia factor (MLF) protein family with multiple alternatively spliced transcript variants encoding different protein isoforms. In hematopoietic cells, it is located mainly in the nucleus, and in non-hematopoietic cells, primarily in the cytoplasm with a punctate nuclear localization. MLF1 plays a role in cell cycle differentiation.
Terms: Myeloid Cell Leukemia Sequence 1 Protein Preferred Term
Term UI T839012
Date03/22/2013
LexicalTag NON
ThesaurusID NLM (2014); Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1
Term UI T839013
Date03/22/2013
LexicalTag NON
ThesaurusID NLM (2014); Myeloid Cell Leukemia Sequence 1
Term UI T839014
Date03/22/2013
LexicalTag NON
ThesaurusID NLM (2014); Myeloid Cell Factor-1
Term UI T839015
Date03/22/2013
LexicalTag NON
ThesaurusID NLM (2014)

Myeloid Cell Leukemia Sequence 1 Protein MeSH Descriptor Data 2025