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Activation, Metabolic
MeSH Descriptor Data 2025
Details
Qualifiers
MeSH Tree Structures
Concepts
MeSH Heading
Activation, Metabolic
Tree Number(s)
G03.171.224
G03.787.225.224
G07.690.725.225.224
Unique ID
D065767
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D065767
Annotation
restrict to chemical changes of exogenous substances; IM general only; coordinate NIM with specific drug
/pharmacokin
(IM) or
/metab
(IM)
Scope Note
The conversion of an exogenous substance by a biological system resulting in the production on an active metabolite.
Entry Version
ACTIVATION METAB
Entry Term(s)
Drug Activation
Metabolic Activation
Previous Indexing
Biotransformation (1976-2014)
Public MeSH Note
2015; see Biotransformation 1980-2014
History Note
2015; use Biotransformation 1980-2014
Date Established
2015/01/01
Date of Entry
2014/06/26
Revision Date
2016/05/02
Allowable Qualifiers
drug effects (DE)
genetics (GE)
immunology (IM)
physiology (PH)
radiation effects (RE)
Metabolism [G03]
Biotransformation [G03.171]
Activation, Metabolic [G03.171.224]
Inactivation, Metabolic [G03.171.450]
Metabolism [G03]
Pharmacokinetics [G03.787]
Biotransformation [G03.787.225]
Activation, Metabolic [G03.787.225.224]
Inactivation, Metabolic [G03.787.225.450]
Physiological Phenomena [G07]
Pharmacological and Toxicological Phenomena [G07.690]
Pharmacokinetics [G07.690.725]
Biotransformation [G07.690.725.225]
Activation, Metabolic [G07.690.725.225.224]
Inactivation, Metabolic [G07.690.725.225.450]
Expand All
Collapse All
Activation, Metabolic
Preferred
Concept UI
M0002567
Scope Note
The conversion of an exogenous substance by a biological system resulting in the production on an active metabolite.
Terms
Activation, Metabolic
Preferred Term
Term UI
T004974
Date
05/21/1991
LexicalTag
NON
ThesaurusID
NLM (1992)
Metabolic Activation
Term UI
T004975
Date
05/30/1979
LexicalTag
NON
ThesaurusID
UNK (19XX)
Drug Activation
Narrower
Concept UI
M0590130
Terms
Drug Activation
Preferred Term
Term UI
T852851
Date
01/02/2014
LexicalTag
NON
ThesaurusID
NLM (2015)
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