MeSH Browser

MeSH Heading: Ofloxacin
Tree Number(s): D03.633.100.810.835.322.500
Unique ID: D015242
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015242
Scope Note: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
Entry Term(s): DL-8280; DR-3355; Hoe-280; ORF-28489; Ofloxacin Hydrochloride; Ofloxacine; Ru-43280; Tarivid
Pharm Action: Anti-Infective Agents, Urinary
Anti-Bacterial Agents
Topoisomerase II Inhibitors
Cytochrome P-450 CYP1A2 Inhibitors
Registry Numbers: A4P49JAZ9H; 0; I2UWV315WA
Related Numbers: 100986-86-5; 118120-51-7; 82419-36-1; 86784-41-0; I2UWV315WA
CAS Type 1 Name: (+/-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7- -oxo-7H-pyrido(1,2,3-de)- -1,4-benzoxazine-6-carboxylic acid
NLM Classification #: QV 250
Previous Indexing: Anti-Infective Agents (1981-1988); Anti-Infective Agents, Urinary (1981-1988); Oxazines (1981-1988)
Public MeSH Note: 89
History Note: 89
Date Established: 1989/01/01
Date of Entry: 1988/05/16
Revision Date: 2016/05/31

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Ofloxacin MeSH Descriptor Data 2024