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Ofloxacin MeSH Descriptor Data 2021


MeSH Heading
Ofloxacin
Tree Number(s)
D03.633.100.810.835.322.500
Unique ID
D015242
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D015242
Scope Note
A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
Entry Term(s)
DL-8280
DR-3355
Hoe-280
ORF-28489
Ofloxacin Hydrochloride
Ofloxacine
Ru-43280
Tarivid
Pharm Action
Anti-Infective Agents, Urinary
Anti-Bacterial Agents
Topoisomerase II Inhibitors
Cytochrome P-450 CYP1A2 Inhibitors
Registry Number
A4P49JAZ9H
Related Numbers
100986-86-5
118120-51-7
82419-36-1
86784-41-0
I2UWV315WA
CAS Type 1 Name
(+/-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7- -oxo-7H-pyrido(1,2,3-de)- -1,4-benzoxazine-6-carboxylic acid
NLM Classification #
QV 250
Previous Indexing
Anti-Infective Agents (1981-1988)
Anti-Infective Agents, Urinary (1981-1988)
Oxazines (1981-1988)
Public MeSH Note
89
History Note
89
Date Established
1989/01/01
Date of Entry
1988/05/16
Revision Date
2016/05/31
Ofloxacin Preferred
Tarivid Narrower
ORF-28489 Narrower
DR-3355 Narrower
Hoe-280 Narrower
Ofloxacin Hydrochloride Narrower
Ru-43280 Narrower
DL-8280 Narrower
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