MeSH Browser

MeSH Heading: Norfloxacin
Tree Number(s): D03.633.100.810.835.322.374
Unique ID: D009643
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D009643
Scope Note: A synthetic fluoroquinolone (FLUOROQUINOLONES) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA GYRASE.
Entry Term(s): AM-0715; AM-715; MK-0366; MK-366; MK0366; MK366; Noroxin
Pharm Action: Anti-Bacterial Agents
Topoisomerase II Inhibitors
Cytochrome P-450 CYP1A2 Inhibitors
Registry Number: N0F8P22L1P
Related Numbers: 70458-96-7
CAS Type 1 Name: 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-
NLM Classification #: QV 250
Previous Indexing: Anti-Infective Agents (1966-1985); Anti-Infective Agents, Urinary (1966-1985); Nalidixic Acid (1966-1985)
Public MeSH Note: 86
History Note: 86
Date Established: 1986/01/01
Date of Entry: 1985/06/06
Revision Date: 2017/05/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0353994
Registry Number: 0
Terms: MK-0366 Preferred Term
Term UI T028703
Date06/06/1985
LexicalTag LAB
ThesaurusID UNK (19XX); MK-366
Term UI T028704
Date06/06/1985
LexicalTag LAB
ThesaurusID UNK (19XX); MK0366
Term UI T028700
Date06/06/1985
LexicalTag LAB
ThesaurusID UNK (19XX); MK366
Term UI T028701
Date06/06/1985
LexicalTag LAB
ThesaurusID UNK (19XX)

Norfloxacin MeSH Descriptor Data 2023