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Pemetrexed MeSH Descriptor Data 2022


MeSH Heading
Pemetrexed
Tree Number(s)
D03.633.100.759.758.399.454.650
D12.125.067.625.525
D12.125.119.409.525
Unique ID
D000068437
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000068437
Scope Note
A guanine-derived ANTINEOPLASTIC AGENT that functions as a NUCLEIC ACID SYNTHESIS INHIBITOR through its binding to, and inhibition of, THYMIDYLATE SYNTHASE.
Entry Term(s)
Alimta
LY 231,514
LY 231514
LY-231,514
LY-231514
LY231514
MTA
N-(4-(2-(2-amino-3,4-dihydro-4-oxo-7H-pyrrolo(2,3-d)pyrimdin-5-yl)ethyl)benzoyl)glutamic acid
Pemetrexed Disodium
Pharm Action
Antineoplastic Agents
Enzyme Inhibitors
Folic Acid Antagonists
Nucleic Acid Synthesis Inhibitors
Registry Number
04Q9AIZ7NO
Related Numbers
137281-23-3
2PKU919BA9
CAS Type 1 Name
L-Glutamic acid, N-(4-(2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo(2,3-d)pyrimidin-5-yl)ethyl)benzoyl)-
Public MeSH Note
2016; PEMETREXED was indexed under GLUTAMATES 1994-2015, and under GUANINE 1994-2015
History Note
2016 (1994)
Date Established
2016/01/01
Date of Entry
2015/07/01
Revision Date
2016/05/31
Pemetrexed Preferred
Pemetrexed Disodium Narrower
LY 231514 Narrower
Alimta Narrower
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