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Trefoil Factor-2 MeSH Descriptor Data 2023

MeSH Heading
Trefoil Factor-2
Tree Number(s)
Unique ID
RDF Unique Identifier
Scope Note
A 106 amino acid (12 kDa) trefoil factor that contains two trefoil domains and associates with MUCIN-6. It is expressed in the GASTROINTESTINAL TRACT by cells of BRUNNER GLANDS; PYLORIC GLANDS and mucous neck cells. It inhibits GASTROINTESTINAL MOTILITY and GASTRIC ACID secretion and may help maintain the structural integrity of gastric mucus.
Entry Term(s)
TFF2 Peptide
TFF2 Protein
Registry Number
Public MeSH Note
2017; TREFOIL FACTOR-2 was indexed under PEPTIDES 2005-2016; under MUCINS 1992-2005; under MUSCLE PROTEINS 1992-2005; and under GROWTH SUBSTANCES 1992-2003
History Note
2017 (1992)
Date Established
Date of Entry
Revision Date
Trefoil Factor-2 Preferred
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