MeSH Browser

MeSH Heading: NF-KappaB Inhibitor alpha
Tree Number(s): D12.644.360.365.500; D12.776.260.420.500; D12.776.476.381.500; D12.776.930.326.500
Unique ID: D000072000
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000072000
Scope Note: An I-kappa B protein that inhibits the activity of dimeric NF-KAPPA B P50-REL complexes, sequesters transcription factor NF-kappaB as an inactive complex in the cytoplasm; and prevents NF-kappaB nuclear translocation and DNA binding.
Entry Term(s): I Kappa B-alpha Protein; IKappaB-alpha; IKappaBalpha; Major Histocompatibility Complex Enhancer-Binding Protein MAD3; p40 Protein (IKappaB-alpha)
See Also: Ankyrin Repeat
Public MeSH Note: 2017; NF-KAPPAB INHIBITOR ALPHA was indexed under DNA-BINDING PROTEINS 1999-2002 and under I-KAPPA B PROTEINS 2003-2016
History Note: 2017 (1991)
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2017/06/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0190194
Scope Note: An I-kappa B protein that inhibits the activity of dimeric NF-KAPPA B P50-REL complexes, sequesters transcription factor NF-kappaB as an inactive complex in the cytoplasm; and prevents NF-kappaB nuclear translocation and DNA binding.
Terms: NF-KappaB Inhibitor alpha Preferred Term
Term UI T000897846
Date03/29/2016
LexicalTag NON
ThesaurusID NLM (2017); I Kappa B-alpha Protein
Term UI T000897847
Date03/29/2016
LexicalTag NON
ThesaurusID NLM (2017); IKappaBalpha
Term UI T000897848
Date03/29/2016
LexicalTag NON
ThesaurusID NLM (2017); IKappaB-alpha
Term UI T000897849
Date03/29/2016
LexicalTag NON
ThesaurusID NLM (2017); p40 Protein (IKappaB-alpha)
Term UI T000897851
Date03/29/2016
LexicalTag NON
ThesaurusID NLM (2017); Major Histocompatibility Complex Enhancer-Binding Protein MAD3
Term UI T000897852
Date03/29/2016
LexicalTag NON
ThesaurusID NLM (2017)

NF-KappaB Inhibitor alpha MeSH Descriptor Data 2025