MeSH Browser

MeSH Heading: Dual Oxidases
Tree Number(s): D08.811.682.608.575.500; D12.776.331.894.500; D12.776.543.653.500
Unique ID: D000074623
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000074623
Scope Note: NADPH oxidases that contain two additional EF HAND MOTIFS and an N-terminal PEROXIDASE domain. They are expressed by THYROCYTES and EPITHELIAL CELLS of the kidney, liver, trachea, lung, and glandular tissues such as the testis, pancreas, and prostate. They are critical for the activity of THYROID PEROXIDASE and play a role in the production of thyroid hormones; they may also have antimicrobial activity through the generation of REACTIVE OXYGEN SPECIES.
Entry Term(s): DUOX1; DUOX2; Dual Oxidase; Dual Oxidase 1; Dual Oxidase 2; Duox Proteins; NADPH Thyroid Oxidase 2; Thyroid Oxidase 2
Related Numbers: EC 1.6.3.1
Previous Indexing: NADPH Oxidases (2001-2017)
Public MeSH Note: 2018
History Note: 2018
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000627203
Related Numbers: EC 1.6.3.1
Scope Note: NADPH oxidases that contain two additional EF HAND MOTIFS and an N-terminal PEROXIDASE domain. They are expressed by THYROCYTES and EPITHELIAL CELLS of the kidney, liver, trachea, lung, and glandular tissues such as the testis, pancreas, and prostate. They are critical for the activity of THYROID PEROXIDASE and play a role in the production of thyroid hormones; they may also have antimicrobial activity through the generation of REACTIVE OXYGEN SPECIES.
Terms: Dual Oxidases Preferred Term
Term UI T000916697
Date03/03/2017
LexicalTag NON
ThesaurusID NLM (2018); Dual Oxidase
Term UI T001007760
Date02/11/2020
LexicalTag NON
ThesaurusID NLM (2021); Duox Proteins
Term UI T000916698
Date03/03/2017
LexicalTag ABX
ThesaurusID NLM (2018)

Concept UI: M000627204
Terms: Dual Oxidase 2 Preferred Term
Term UI T000916699
Date03/03/2017
LexicalTag NON
ThesaurusID NLM (2018); DUOX2
Term UI T000916700
Date03/03/2017
LexicalTag ABB
ThesaurusID NLM (2018); NADPH Thyroid Oxidase 2
Term UI T000916701
Date03/03/2017
LexicalTag ABX
ThesaurusID NLM (2018); Thyroid Oxidase 2
Term UI T000916702
Date03/03/2017
LexicalTag NON
ThesaurusID NLM (2018)

Dual Oxidases MeSH Descriptor Data 2025