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Immunoglobulin Light-chain Amyloidosis MeSH Descriptor Data 2025


MeSH Heading
Immunoglobulin Light-chain Amyloidosis
Tree Number(s)
C04.557.595.250
C18.452.845.500.550
C20.683.515.507
C20.683.780.565
Unique ID
D000075363
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000075363
Scope Note
A nonproliferative disorder of PLASMA CELLS characterized by excessive production and misfolding of IMMUNOGLOBULIN LIGHT CHAINS that form insoluble amyloid fibrils (see AMYLOID DEPOSITS) in various tissues. Clinical features include LIVER FAILURE; MULTIPLE MYELOMA; NEPHROTIC SYNDROME; RESTRICTIVE CARDIOMYOPATHY, and neuropathies.
Entry Term(s)
AL Amyloidosis
Amyloidosis, Immunoglobulin Light-chain
Amyloidosis, Primary
Monoclonal Immunoglobulin Deposition Disease
Primary Amyloidosis
Primary Systemic Amyloidosis
Public MeSH Note
2018; PRIMARY AMYLOIDOSIS was indexed under AMYLOIDOSIS 2010-2017
History Note
2018(2010)
Date Established
2018/01/01
Date of Entry
2017/07/11
Revision Date
2023/06/09
Immunoglobulin Light-chain Amyloidosis Preferred
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