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Immunoproliferative Small Intestinal Disease MeSH Descriptor Data 2025


MeSH Heading
Immunoproliferative Small Intestinal Disease
Tree Number(s)
C04.557.386.390
C06.301.371.411.512
C06.405.249.411.512
C06.405.469.491.505
C15.378.147.780.490.512
C15.604.515.435.512
C20.683.515.512
C20.683.780.490.512
Unique ID
D007161
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D007161
Scope Note
A condition that is caused by HYPERPLASIA of LYMPHOCYTES in the small intestine (INTESTINE, SMALL) and the mesenteric LYMPH NODES. These lymphocytes produce an anomalous alpha heavy chain protein. Generally, these IPSID patients have either concurrent LYMPHOMA or develop lymphoma within a few years. The disease was first described in the Mediterranean region and is characterized by malabsorption; WEIGHT LOSS; DIARRHEA; and STEATORRHEA.
Entry Version
IMMUNOPROLIFERATIVE SMALL INTESTINAL DIS
Entry Term(s)
Heavy Chain Disease, IgA Type
IPSID
Lymphoma, Mediterranean
alpha-Chain Disease
Previous Indexing
Heavy Chain Disease (1966-1986)
Intestinal Neoplasms (1966-1986)
Lymphoma (1966-1986)
Public MeSH Note
87
History Note
87
Date Established
1987/01/01
Date of Entry
1986/06/24
Revision Date
2018/06/29
Immunoproliferative Small Intestinal Disease Preferred
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