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Olanzapine
MeSH Descriptor Data 2025
Details
Qualifiers
MeSH Tree Structures
Concepts
MeSH Heading
Olanzapine
Tree Number(s)
D03.633.100.079.080.738
Unique ID
D000077152
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077152
Scope Note
A benzodiazepine derivative that binds
SEROTONIN RECEPTORS
;
MUSCARINIC RECEPTORS
;
HISTAMINE H1 RECEPTORS
;
ADRENERGIC ALPHA-1 RECEPTORS
; and
DOPAMINE RECEPTORS
. It is an antipsychotic agent used in the treatment of
SCHIZOPHRENIA
;
BIPOLAR DISORDER
; and
MAJOR DEPRESSIVE DISORDER
; it may also reduce nausea and vomiting in patients undergoing chemotherapy.
Entry Term(s)
2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno(2,3-b)(1,5)benzodiazepine
LY 170053
LY-170052
Olanzapine Pamoate
Zolafren
Zyprexa
Pharm Action
Antiemetics
Antipsychotic Agents
Selective Serotonin Reuptake Inhibitors
Related Numbers
X7S6Q4MHCB
Public MeSH Note
2019; OLANZAPINE was indexed under BENZODIAZEPINES 1992-2018
History Note
2019 (1992)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2022/07/18
Allowable Qualifiers
administration & dosage (AD)
adverse effects (AE)
agonists (AG)
analogs & derivatives (AA)
analysis (AN)
antagonists & inhibitors (AI)
blood (BL)
cerebrospinal fluid (CF)
chemical synthesis (CS)
chemistry (CH)
classification (CL)
economics (EC)
history (HI)
immunology (IM)
isolation & purification (IP)
metabolism (ME)
pharmacokinetics (PK)
pharmacology (PD)
poisoning (PO)
radiation effects (RE)
standards (ST)
supply & distribution (SD)
therapeutic use (TU)
toxicity (TO)
urine (UR)
Heterocyclic Compounds [D03]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Benzazepines [D03.633.100.079]
Benzodiazepines [D03.633.100.079.080]
Alprazolam [D03.633.100.079.080.030]
Benzodiazepinones [D03.633.100.079.080.070]
Chlordiazepoxide [D03.633.100.079.080.150]
Clobazam [D03.633.100.079.080.165]
Clorazepate Dipotassium [D03.633.100.079.080.180]
Estazolam [D03.633.100.079.080.250]
Medazepam [D03.633.100.079.080.550]
Midazolam [D03.633.100.079.080.575]
Olanzapine [D03.633.100.079.080.738]
Triazolam [D03.633.100.079.080.900]
Expand All
Collapse All
Olanzapine
Preferred
Concept UI
M0204623
Related Numbers
X7S6Q4MHCB
Scope Note
A benzodiazepine derivative that binds
SEROTONIN RECEPTORS
;
MUSCARINIC RECEPTORS
;
HISTAMINE H1 RECEPTORS
;
ADRENERGIC ALPHA-1 RECEPTORS
; and
DOPAMINE RECEPTORS
. It is an antipsychotic agent used in the treatment of
SCHIZOPHRENIA
;
BIPOLAR DISORDER
; and
MAJOR DEPRESSIVE DISORDER
; it may also reduce nausea and vomiting in patients undergoing chemotherapy.
Terms
Olanzapine
Preferred Term
Term UI
T000937046
Date
12/01/2017
LexicalTag
NON
ThesaurusID
2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno(2,3-b)(1,5)benzodiazepine
Term UI
T000937047
Date
12/01/2017
LexicalTag
NON
ThesaurusID
NLM (1992)
LY 170053
Narrower
Concept UI
M0204620
Terms
LY 170053
Preferred Term
Term UI
T234625
Date
01/01/1955
LexicalTag
LAB
ThesaurusID
NLM (1992)
LY-170052
Narrower
Concept UI
M0204621
Terms
LY-170052
Preferred Term
Term UI
T234626
Date
01/01/1955
LexicalTag
LAB
ThesaurusID
NLM (1992)
Zyprexa
Narrower
Concept UI
M0204622
Terms
Zyprexa
Preferred Term
Term UI
T234627
Date
01/01/1955
LexicalTag
TRD
ThesaurusID
Olanzapine Pamoate
Narrower
Concept UI
M0535637
Terms
Olanzapine Pamoate
Preferred Term
Term UI
T000937050
Date
12/01/2017
LexicalTag
NON
ThesaurusID
Zolafren
Narrower
Concept UI
M000639460
Terms
Zolafren
Preferred Term
Term UI
T000900245
Date
05/02/2016
LexicalTag
TRD
ThesaurusID
NLM (2016)
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