MeSH Browser

MeSH Heading: Olanzapine
Tree Number(s): D03.633.100.079.080.738
Unique ID: D000077152
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000077152
Scope Note: A benzodiazepine derivative that binds SEROTONIN RECEPTORS; MUSCARINIC RECEPTORS; HISTAMINE H1 RECEPTORS; ADRENERGIC ALPHA-1 RECEPTORS; and DOPAMINE RECEPTORS. It is an antipsychotic agent used in the treatment of SCHIZOPHRENIA; BIPOLAR DISORDER; and MAJOR DEPRESSIVE DISORDER; it may also reduce nausea and vomiting in patients undergoing chemotherapy.
Entry Term(s): 2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno(2,3-b)(1,5)benzodiazepine; LY 170053; LY-170052; Olanzapine Pamoate; Zolafren; Zyprexa
Pharm Action: Antiemetics
Antipsychotic Agents
Selective Serotonin Reuptake Inhibitors
Related Numbers: X7S6Q4MHCB
Public MeSH Note: 2019; OLANZAPINE was indexed under BENZODIAZEPINES 1992-2018
History Note: 2019 (1992)
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2022/07/18

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Olanzapine MeSH Descriptor Data 2025