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Wortmannin MeSH Descriptor Data 2023


MeSH Heading
Wortmannin
Tree Number(s)
D04.210.500.054.079.129.891
Unique ID
D000077191
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077191
Scope Note
An androstadiene metabolite produced by the fungi PENICILLIUM funiculosum that inhibits PHOSPHATIDYLINOSITOL-3-KINASES and alloantigen-specific activation of T-LYMPHOCYTES in human tumor cell lines. It is widely used in CELL BIOLOGY research and has broad therapeutic potential.
Entry Term(s)
MS 54
MS-54
Pharm Action
Antifungal Agents
Immunosuppressive Agents
Insulin Antagonists
Radiation-Sensitizing Agents
Protein Kinase Inhibitors
Registry Number
XVA4O219QW
Related Numbers
19545-26-7
CAS Type 1 Name
(1 alpha,11 alpha)-11-(Acetyloxy)-1-(methoxymethyl)-2-oxaandrosta-5,8-dieno(6,5,4-bc)furan- 3,7,17-trione
Public MeSH Note
2019; WORTMANNIN was indexed under ANDROSTADIENES 1980-2018, and under COUMARINS and INDENES 1974-1979
History Note
2019 (1974)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2018/06/19
Wortmannin Preferred
MS 54 Narrower
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