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Lapatinib MeSH Descriptor Data 2021


MeSH Heading
Lapatinib
Tree Number(s)
D03.633.100.786.516
Unique ID
D000077341
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077341
Scope Note
A quinazoline derivative that inhibits EPIDERMAL GROWTH FACTOR RECEPTOR and HER2 (RECEPTOR, ERBB-2) tyrosine kinases. It is used for the treatment of advanced or metastatic breast cancer, where tumors overexpress HER2.
Entry Term(s)
GW 282974X
GW 572016
GW-282974X
GW-572016
GW282974X
GW572016
Lapatinib Ditosylate
N-(3-chloro-4-(((3-fluorobenzyl)oxy)phenyl)-6-(5-(((2-methylsulfonyl)ethyl)amino)methyl) -2-furyl)-4-quinazolinamine
Tykerb
Pharm Action
Antineoplastic Agents
Protein Kinase Inhibitors
Registry Number
0VUA21238F
Related Numbers
G873GX646R
Public MeSH Note
2019; LAPATINIB was indexed under QUINAZOLINES 2004-2018
History Note
2019 (2004)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2018/07/03
Lapatinib Preferred
Tykerb Narrower
GW 282974X Narrower
GW572016 Narrower
Lapatinib Ditosylate Narrower
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