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2-Methoxyestradiol MeSH Descriptor Data 2023


MeSH Heading
2-Methoxyestradiol
Tree Number(s)
D04.210.500.365.415.248.830
D06.472.334.851.437.500.750
Unique ID
D000077584
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077584
Scope Note
A metabolite of estradiol that lacks estrogenic activity and inhibits TUBULIN polymerization. It has antineoplastic properties, including inhibition of angiogenesis and induction of APOPTOSIS.
Entry Term(s)
(17 beta)-2-methoxyestra-1,3,5(10)-triene-3,17-diol
2-(methyl-11C)Methoxyestradiol
2-Methoxyestradiol, (17alpha)-isomer
2-Methoxyestradiol-17 beta
2-Methoxyoestradiol
Panzem
Pharm Action
Antineoplastic Agents
Tubulin Modulators
Registry Number
6I2QW73SR5
Related Numbers
10332-20-4
362-07-2
CAS Type 1 Name
Estra-1,3,5(10)-triene-3,17-diol, 2-methoxy-, (17beta)-
Public MeSH Note
2019; 2-METHOXYESTRADIOL was indexed under ESTRADIOL/analogs & derivatives 1980-2018
History Note
2019 (1980)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2018/04/09
2-Methoxyestradiol Preferred
2-Methoxyestradiol-17 beta Narrower
2-Methoxyestradiol, (17alpha)-isomer Narrower
2-(methyl-11C)Methoxyestradiol Narrower
Panzem Narrower
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