MeSH Browser

MeSH Heading: Estradiol
Tree Number(s): D04.210.500.365.415.248; D06.472.334.851.437.500
Unique ID: D004958
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D004958
Annotation: for /‌antag also consider: ESTROGEN RECEPTOR MODULATORS; ESTROGEN RECEPTOR ANTAGONISTS; and AROMATASE INHIBITORS.
Scope Note: The 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids.
Entry Term(s): 17 beta-Estradiol; 17 beta-Oestradiol; Aerodiol; Delestrogen; Estrace; Estraderm TTS; Estradiol Anhydrous; Estradiol Hemihydrate; Estradiol Hemihydrate, (17 alpha)-Isomer; Estradiol Monohydrate; Estradiol Valerate; Estradiol Valeriante; Estradiol, (+-)-Isomer; Estradiol, (-)-Isomer; Estradiol, (16 alpha,17 alpha)-Isomer; Estradiol, (16 alpha,17 beta)-Isomer; Estradiol, (17-alpha)-Isomer; Estradiol, (8 alpha,17 beta)-(+-)-Isomer; Estradiol, (8 alpha,17 beta)-Isomer; Estradiol, (9 beta,17 alpha)-Isomer; Estradiol, (9 beta,17 beta)-Isomer; Estradiol, Monosodium Salt; Estradiol, Sodium Salt; Estradiol-17 alpha; Estradiol-17 beta; Estradiol-17beta; Oestradiol; Ovocyclin; Progynon-Depot; Progynova; Vivelle
Pharm Action: Estrogens
Related Numbers: 15399-28-7; 17181-19-0; 17916-67-5; 18290-08-9; 19518-62-8; 19669-82-0; 35380-71-3; 3736-22-9; 50-28-2; 517-04-4; 5864-38-0; 6045-52-9; 63667-07-2; 95463-67-5; 979-32-8; CXY7B3Q98Z; OKG364O896
CAS Type 1 Name: Estra-1,3,5(10)-triene-3,17-diol (17beta)-
NLM Classification #: WP 522
See Also: Receptors, Estradiol
Public MeSH Note: 1963; OVOCYCLIN was indexed under ESTRADIOL/analogs & derivatives 1980-1998; /therapeutic use was ESTRADIOL, THERAPEUTIC 1965
History Note: 1963; for OVOCYCLIN use ESTRADIOL DIPROPIONATE (NM) 1980-1998; /therapeutic use was ESTRADIOL, THERAPEUTIC 1965
Entry Combination: antagonists & inhibitors:Estrogen Antagonists
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2018/04/09

Entry Combination: antagonists & inhibitors:Estrogen Antagonists
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Polycyclic Compounds [D04]
- Fused-Ring Compounds [D04.210]
  - Steroids [D04.210.500]
    - Estranes [D04.210.500.365]
      - Estrenes [D04.210.500.365.415]
        
        Allylestrenol [D04.210.500.365.415.050]
        
        Epimestrol [D04.210.500.365.415.200]
        
        Equilenin [D04.210.500.365.415.215]
        
        Equilin [D04.210.500.365.415.220]
        
        Estradiol [D04.210.500.365.415.248]
        
        Estramustine [D04.210.500.365.415.248.320]
        
        Fulvestrant [D04.210.500.365.415.248.660]
        
        2-Methoxyestradiol [D04.210.500.365.415.248.830]
        
        Estriol [D04.210.500.365.415.331]
        
        Estrone [D04.210.500.365.415.414]
        
        Metribolone [D04.210.500.365.415.550]
        
        Mifepristone [D04.210.500.365.415.580]
        
        Nandrolone [D04.210.500.365.415.638]
        
        Trenbolone Acetate [D04.210.500.365.415.930]

Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
- Hormones [D06.472]
  - Gonadal Hormones [D06.472.334]
    - Gonadal Steroid Hormones [D06.472.334.851]
      - Estradiol Congeners [D06.472.334.851.437]
        
        Equilenin [D06.472.334.851.437.249]
        
        Equilin [D06.472.334.851.437.374]
        
        Estradiol [D06.472.334.851.437.500]
        
        Fulvestrant [D06.472.334.851.437.500.500]
        
        2-Methoxyestradiol [D06.472.334.851.437.500.750]
        
        Estriol [D06.472.334.851.437.750]
        
        Estrogenic Steroids, Alkylated [D06.472.334.851.437.968]
        
        Estrogens, Catechol [D06.472.334.851.437.984]
        
        Estrogens, Conjugated (USP) [D06.472.334.851.437.988]
        
        Estrogens, Esterified (USP) [D06.472.334.851.437.994]
        
        Estrone [D06.472.334.851.437.996]

Estradiol Preferred

Concept UI: M0007772
Related Numbers: 15399-28-7; 17181-19-0; 17916-67-5; 18290-08-9; 19518-62-8; 19669-82-0; 35380-71-3; 3736-22-9; 50-28-2; 517-04-4; 5864-38-0; 6045-52-9; 63667-07-2; 95463-67-5; 979-32-8; CXY7B3Q98Z; OKG364O896
Scope Note: The 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids.
Terms: Estradiol Preferred Term
Term UI T015123
Date01/01/1999
LexicalTag NON
ThesaurusID; Estradiol Anhydrous
Term UI T858881
Date04/22/2014
LexicalTag NON
ThesaurusID NLM (2015); Estradiol-17beta
Term UI T525667
Date11/07/2002
LexicalTag NON
ThesaurusID NLM (2004); Estradiol-17 beta
Term UI T015122
Date05/31/1983
LexicalTag NON
ThesaurusID UNK (19XX); 17 beta-Oestradiol
Term UI T015124
Date08/07/1981
LexicalTag NON
ThesaurusID UNK (19XX); Oestradiol
Term UI T015125
Date12/22/1997
LexicalTag NON
ThesaurusID; 17 beta-Estradiol
Term UI T015121
Date05/31/1983
LexicalTag NON
ThesaurusID UNK (19XX)