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Doripenem MeSH Descriptor Data 2022


MeSH Heading
Doripenem
Tree Number(s)
D02.065.589.099.124.150
D03.633.100.300.124.150
Unique ID
D000077726
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077726
Scope Note
A carbapenem derivative antibacterial agent that is more stable to renal dehydropeptidase I than IMIPENEM, but does not need to be given with an enzyme inhibitor such as CILASTATIN. It is used in the treatment of infections such as HOSPITAL-ACQUIRED PNEUMONIA, and complicated intra-abdominal or urinary-tract infections, including PYELONEPHRITIS.
Entry Term(s)
2-(5-sulfamoylaminomethylpyrrolidin-3-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapen-2-em-3-carboxylic acid
S 4661
S-4661
Pharm Action
Anti-Bacterial Agents
Registry Number
BHV525JOBH
CAS Type 1 Name
1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-(((3S,5S)-5-(((aminosulfonyl)amino)methyl)-3-pyrrolidinyl)thio)-6-((1R)-1-hydroxyethyl)-4-methyl-7-oxo-, (4R,5S,6S)-
Public MeSH Note
2019; DORIPENEM was indexed under CARBAPENEMS 1996-2018
History Note
2019 (1996)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2018/04/10
Doripenem Preferred
2-(5-sulfamoylaminomethylpyrrolidin-3-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapen-2-em-3-carboxylic acid Narrower
S 4661 Narrower
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