NLM Logo

Imipenem MeSH Descriptor Data 2023


MeSH Heading
Imipenem
Tree Number(s)
D02.065.589.099.124.300.500
D03.633.100.300.124.300.500
Unique ID
D015378
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D015378
Scope Note
Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with CILASTATIN, a renal dipeptidase inhibitor.
Entry Term(s)
Imipemide
Imipenem Anhydrous
Imipenem, Anhydrous
MK-0787
MK0787
N-Formimidoylthienamycin
Pharm Action
Anti-Bacterial Agents
Registry Number
71OTZ9ZE0A
Related Numbers
74431-23-5
Q20IM7HE75
CAS Type 1 Name
1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-3-((2-((iminomethyl)amino)ethyl)thio)-7-oxo-, (5R-(5alpha,6alpha(R*)))-
NLM Classification #
QV 350
Previous Indexing
Antibiotics (1980-1982)
Thienamycins (1983-1988)
Public MeSH Note
89
History Note
89
Date Established
1989/01/01
Date of Entry
1988/06/03
Revision Date
2016/05/31
Imipenem Preferred
Imipenem, Anhydrous Narrower
MK-0787 Narrower
page delivered in 0.19s