MeSH Browser

MeSH Heading: Lacosamide
Tree Number(s): D02.065.064.416; D02.241.081.018.110.432
Unique ID: D000078334
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000078334
Scope Note: An acetamide derivative that acts as a blocker of VOLTAGE-GATED SODIUM CHANNELS. It is used as an anticonvulsant, for adjunctive or monotherapy, in the treatment of PARTIAL SEIZURES.
Entry Term(s): N-benzyl-2-acetamido-3-methoxypropionamide; N-benzyl-AcMeOPrNH2; Vimpat
Pharm Action: Anticonvulsants
Voltage-Gated Sodium Channel Blockers
Registry Number: 563KS2PQY5
CAS Type 1 Name: Propanamide, 2-(acetylamino)-3-methoxy-N-(phenylmethyl)-, (2R)-
Public MeSH Note: 2019; LACOSAMIDE was indexed under ACETAMIDES 2000-2019
History Note: 2019 (2000)
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/05/21

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Lacosamide MeSH Descriptor Data 2023