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2-Acetylaminofluorene MeSH Descriptor Data 2025


MeSH Heading
2-Acetylaminofluorene
Tree Number(s)
D02.065.064.150
D02.241.081.018.110.080
D02.455.426.559.847.389.050
D04.615.389.050
Unique ID
D015073
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D015073
Scope Note
A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
Entry Term(s)
2-AAF
2-Acetamidofluorene
2-Fluorenylacetamide
AAF, Aminofluorene
Acetylaminofluorene
Fluoren-2-ylacetamide
N-2-Fluorenylacetamide
N-Acetyl-2-Aminofluorene
Pharm Action
Carcinogens
Related Numbers
53-96-3
CAS Type 1 Name
Acetamide, N-9H-fluoren-2-yl-
Previous Indexing
Acetamides (1971-1974)
Fluorenes (1966-1974)
Public MeSH Note
83; was ACETYLAMINOFLUORENE 1980-82; was ACETYLAMINOFLUORENE see under FLUORENES 1975-79
Online Note
use 2-ACETYLAMINOFLUORENE to search ACETYLAMINOFLUORENE 1975-82
History Note
83; was ACETYLAMINOFLUORENE 1980-82; was ACETYLAMINOFLUORENE see under FLUORENES 1975-79
Date Established
1980/01/01
Date of Entry
1974/11/11
Revision Date
2013/07/08
2-Acetylaminofluorene Preferred
Acetylaminofluorene Broader
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