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Brain-Gut Axis MeSH Descriptor Data 2023


MeSH Heading
Brain-Gut Axis
Tree Number(s)
G11.561.138
Unique ID
D000087502
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000087502
Scope Note
An interactive network between the GASTROINTESTINAL TRACT (gut) and the brain principally mediated through the ENTERIC NERVOUS SYSTEM. Control of the gut activities during stress, for instance, is mediated by activation of neuroendocrine hormones (e.g., CORTICOTROPIN-RELEASING FACTOR). Conversely, INTESTINAL MICROBIOTA associate with the CENTRAL NERVOUS SYSTEM through the axis via microorganism-derived products (e.g., UROCORTINS). Some functional GASTROINTESTINAL DISORDERS (e.g., IRRITABLE BOWEL SYNDROME) have dysregulated brain-gut axis.
Entry Term(s)
Brain and Gut Axis
Brain-Gut-Microbiome Axis
Gut and Brain Axis
Gut-Brain Axis
Gut-Brain-Microbiome Axis
Microbiome-Brain-Gut Axis
Microbiome-Gut-Brain Axis
Microbiota-Brain-Gut Axis
Microbiota-Gut-Brain Axis
Previous Indexing
Brain (1980-2021)
Digestive System Physiological Phenomena (1981-2021)
Gastrointestinal Microbiome (2015-2021)
Gastrointestinal Tract (2003-2021)
See Also
Gastrointestinal Microbiome
Public MeSH Note
2022
History Note
2022
Date Established
2022/01/01
Date of Entry
2021/07/09
Revision Date
2021/06/30
Brain-Gut Axis Preferred
Microbiota-Gut-Brain Axis Related
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