MeSH Browser

MeSH Heading: Brain-Gut Axis
Tree Number(s): G11.561.138
Unique ID: D000087502
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000087502
Scope Note: An interactive network between the GASTROINTESTINAL TRACT (gut) and the brain principally mediated through the ENTERIC NERVOUS SYSTEM. Control of the gut activities during stress, for instance, is mediated by activation of neuroendocrine hormones (e.g., CORTICOTROPIN-RELEASING FACTOR). Conversely, INTESTINAL MICROBIOTA associate with the CENTRAL NERVOUS SYSTEM through the axis via microorganism-derived products (e.g., UROCORTINS). Some functional GASTROINTESTINAL DISORDERS (e.g., IRRITABLE BOWEL SYNDROME) have dysregulated brain-gut axis.
Entry Term(s): Brain and Gut Axis; Brain-Gut-Microbiome Axis; Gut and Brain Axis; Gut-Brain Axis; Gut-Brain-Microbiome Axis; Microbiome-Brain-Gut Axis; Microbiome-Gut-Brain Axis; Microbiota-Brain-Gut Axis; Microbiota-Gut-Brain Axis
Previous Indexing: Brain (1980-2021); Digestive System Physiological Phenomena (1981-2021); Gastrointestinal Microbiome (2015-2021); Gastrointestinal Tract (2003-2021)
See Also: Gastrointestinal Microbiome
Public MeSH Note: 2022
History Note: 2022
Date Established: 2022/01/01
Date of Entry: 2021/07/09
Revision Date: 2021/06/30

Allowable Qualifiers: drug effects (DE)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Concept UI: M000738305
Scope Note: An interactive network between the GASTROINTESTINAL TRACT (gut) and the brain principally mediated through the ENTERIC NERVOUS SYSTEM. Control of the gut activities during stress, for instance, is mediated by activation of neuroendocrine hormones (e.g., CORTICOTROPIN-RELEASING FACTOR). Conversely, INTESTINAL MICROBIOTA associate with the CENTRAL NERVOUS SYSTEM through the axis via microorganism-derived products (e.g., UROCORTINS). Some functional GASTROINTESTINAL DISORDERS (e.g., IRRITABLE BOWEL SYNDROME) have dysregulated brain-gut axis.
Terms: Brain-Gut Axis Preferred Term
Term UI T001088344
Date09/09/2020
LexicalTag NON
ThesaurusID NLM (2022); Brain and Gut Axis
Term UI T001088884
Date09/17/2020
LexicalTag NON
ThesaurusID NLM (2022); Gut and Brain Axis
Term UI T001088885
Date09/17/2020
LexicalTag NON
ThesaurusID NLM (2022); Gut-Brain Axis
Term UI T001088345
Date09/09/2020
LexicalTag NON
ThesaurusID NLM (2022)

Concept UI: M000738306
Terms: Microbiota-Gut-Brain Axis Preferred Term
Term UI T001088346
Date09/09/2020
LexicalTag NON
ThesaurusID NLM (2022); Microbiome-Brain-Gut Axis
Term UI T001088347
Date09/09/2020
LexicalTag NON
ThesaurusID NLM (2022); Brain-Gut-Microbiome Axis
Term UI T001088348
Date09/09/2020
LexicalTag NON
ThesaurusID NLM (2022); Microbiota-Brain-Gut Axis
Term UI T001088351
Date09/09/2020
LexicalTag NON
ThesaurusID NLM (2022); Gut-Brain-Microbiome Axis
Term UI T001088349
Date09/09/2020
LexicalTag NON
ThesaurusID NLM (2022); Microbiome-Gut-Brain Axis
Term UI T001088350
Date09/09/2020
LexicalTag NON
ThesaurusID NLM (2022)

Brain-Gut Axis MeSH Descriptor Data 2025