MeSH Browser

MeSH Heading: Mast Cell Activation Disorders
Tree Number(s): C20.762
Unique ID: D000090362
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000090362
Scope Note: A spectrum of primary, secondary, and idiopathic disorders involving MAST CELLS and characterized by an aberrant release of mast cell mediators which result in multiple and variable inflammatory and allergic symptoms. These disorders are associated with various mutations in tyrosine kinase KIT (PROTO-ONCOGENE PROTEINS C-KIT) and other genes, underlying conditions, and responses to allergic or non-allergic triggers of mast cell stimulation and degranulation such as local anesthetics, lactam antibiotics, muscle relaxants, specific foods, environmental toxins, physical conditions such as vibration, cold, pressure, and stress.
Entry Term(s): Clonal Mast Cell Proliferation Disorders; Mast Cell Activation Disease; Mast Cell Disease; Mast-Cell Disease; Monoclonal Mast Cell Activation Syndrome; Primary Mast Cell Activation Disorders
Public MeSH Note: 2022; for MAST CELL ACTIVATION DISEASE see MASTOCYTOSIS 2018-2021
History Note: 2022; for MAST CELL ACTIVATION DISEASE use MASTOCYTOSIS 2018-2021
Date Established: 2022/01/01
Date of Entry: 2021/07/09
Revision Date: 2021/07/07

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

congenital (CN)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Concept UI: M000738446
Scope Note: A spectrum of primary, secondary, and idiopathic disorders involving MAST CELLS and characterized by an aberrant release of mast cell mediators which result in multiple and variable inflammatory and allergic symptoms. These disorders are associated with various mutations in tyrosine kinase KIT (PROTO-ONCOGENE PROTEINS C-KIT) and other genes, underlying conditions, and responses to allergic or non-allergic triggers of mast cell stimulation and degranulation such as local anesthetics, lactam antibiotics, muscle relaxants, specific foods, environmental toxins, physical conditions such as vibration, cold, pressure, and stress.
Terms: Mast Cell Activation Disorders Preferred Term
Term UI T001088625
Date09/14/2020
LexicalTag NON
ThesaurusID NLM (2022); Mast Cell Activation Disease
Term UI T000920141
Date03/27/2017
LexicalTag NON
ThesaurusID NLM (2018); Mast Cell Disease
Term UI T811741
Date11/15/2011
LexicalTag NON
ThesaurusID OMIM (2013); Mast-Cell Disease
Term UI T025030
Date04/07/1986
LexicalTag NON
ThesaurusID

Mast Cell Activation Disorders MeSH Descriptor Data 2025