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Corneal Cross-Linking MeSH Descriptor Data 2025


MeSH Heading
Corneal Cross-Linking
Tree Number(s)
E02.186.500.500
E02.319.685.500
E02.774.722.218
Unique ID
D000094504
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000094504
Scope Note
An ophthalmic treatment used to prevent weakening or bulging of the CORNEA in corneal ECTASIA, e.g., post-LASIK ectasia, KERATOCONUS and pellucid marginal corneal degeneration. It uses UV-A and RIBOFLAVIN to crosslink and strengthen COLLAGEN fibers within the cornea.
Entry Term(s)
Corneal Collagen Cross-Linking
Epi-off CXL
Epi-off Corneal Cross-Linking
Epi-on CXL
Epithelium-off CXL
Epithelium-off Corneal Cross-Linking
Epithelium-on CXL
Epithelium-on Corneal Cross-Linking
Transepithelial CXL
Transepithelial Corneal Cross-Linking
Previous Indexing
Cross-Linking Reagents (2006-2022)
Photochemotherapy (2008-2022)
Public MeSH Note
2023
History Note
2023
Date Established
2023/01/01
Date of Entry
2022/07/12
Revision Date
2022/07/12
Corneal Cross-Linking Preferred
Epithelium-off CXL Narrower
Epithelium-on CXL Narrower
Transepithelial CXL Narrower
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