MeSH Browser

MeSH Heading: Pleuromutilins
Tree Number(s): D02.455.849.291.564
Unique ID: D000097567
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000097567
Scope Note: A tricyclic diterpene natural product isolated from Pleurotus mutilus (now referred to as Clitopilus scyphoides). Possesses modest antibacterial activity against primarily gram-positive bacterial organisms.
Entry Term(s): Drosophilin B; Octahydro-5,8-dihydroxy-4,6,9,10- tetramethyl-6-vinyl-3a,9-propano-3aH-cyclopenta- cycloocten-1(4H)-one 8-glycolate; Pleuromutilin; Pleuromutilin Antibiotics
Pharm Action: Anti-Bacterial Agents
Related Numbers: 125-65-5; 3DE4A80MZ1
Public MeSH Note: 2024: PLEUROMUTILIN was indexed under DITERPENES and POLYCYCLIC COMPOUNDS 1975-2023, and under CYCLOPARAFFINS and GLYCOLATES 1973-1975
History Note: 2024 (1973)
Date Established: 2024/01/01
Date of Entry: 2023/07/26
Revision Date: 2023/06/14

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Pleuromutilins MeSH Descriptor Data 2025