MeSH Browser

MeSH Heading: Retinaldehyde
Tree Number(s): D02.047.850; D02.455.326.271.665.202.495.690; D02.455.426.392.368.367.379.249.700.690; D02.455.849.131.495.690; D02.455.849.291.605; D23.767.261.700.690
Unique ID: D012172
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D012172
Annotation: /biosyn /‌physiol permitted
Scope Note: A diterpene derived from the carotenoid VITAMIN A which functions as the active component of the visual cycle. It is the prosthetic group of RHODOPSIN (i.e., covalently bonded to ROD OPSIN as 11-cis-retinal). When stimulated by visible light, rhodopsin transforms this cis-isomer of retinal to the trans-isomer (11-trans-retinal). This transformation straightens-out the bend of the retinal molecule and causes a change in the shape of rhodopsin triggering the visual process. A series of energy-requiring enzyme-catalyzed reactions convert the 11-trans-retinal back to the cis-isomer.
Entry Term(s): 11-cis-Retinal; 11-trans-Retinal; 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-Nonatetraenal; Axerophthal; Retinal; Retinene; Retinyl Aldehydde; Vitamin A Aldehyde; all-trans-Retinal
Related Numbers: 116-31-4
Public MeSH Note: 91; was see under RETINOIDS 1984-90; was see under VITAMIN A 1968-83
Online Note: search VITAMIN A 1968-74
History Note: 91(75); was see under RETINOIDS 1984-90; was see under VITAMIN A 1968-83
Date Established: 1991/01/01
Date of Entry: 1999/01/01
Revision Date: 2021/07/07

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0018957
Related Numbers: 116-31-4
Scope Note: A diterpene derived from the carotenoid VITAMIN A which functions as the active component of the visual cycle. It is the prosthetic group of RHODOPSIN (i.e., covalently bonded to ROD OPSIN as 11-cis-retinal). When stimulated by visible light, rhodopsin transforms this cis-isomer of retinal to the trans-isomer (11-trans-retinal). This transformation straightens-out the bend of the retinal molecule and causes a change in the shape of rhodopsin triggering the visual process. A series of energy-requiring enzyme-catalyzed reactions convert the 11-trans-retinal back to the cis-isomer.
Terms: Retinaldehyde Preferred Term
Term UI T036225
Date01/01/1999
LexicalTag NON
ThesaurusID; Retinene
Term UI T036226
Date11/05/1974
LexicalTag NON
ThesaurusID UNK (19XX); Retinyl Aldehydde
Term UI T001104346
Date04/09/2021
LexicalTag NON
ThesaurusID NLM (2022); Axerophthal
Term UI T036223
Date11/05/1974
LexicalTag NON
ThesaurusID; Retinal
Term UI T036224
Date11/05/1974
LexicalTag NON
ThesaurusID; 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-Nonatetraenal
Term UI T001096825
Date02/10/2021
LexicalTag NON
ThesaurusID NLM (2022); Vitamin A Aldehyde
Term UI T036227
Date11/05/1974
LexicalTag NON
ThesaurusID

Retinaldehyde MeSH Descriptor Data 2025