MeSH Browser

MeSH Heading: Dectin-1
Tree Number(s): D12.776.503.280.343; D12.776.543.750.705.910.111
Unique ID: D000099181
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000099181
Scope Note: A C-type lectin that functions as a pattern recognition receptor on DENDRITIC CELLS and other immune cells. It is specific for beta-1,-linked and beta 1,6-linked GLUCANS that constitute the CELL WALL of pathogenic bacteria and fungi, and is essential for the TOLL-LIKE RECEPTOR 2 INNATE INFLAMMATORY RESPONSE and activation of NF-KAPPA-B.
Entry Term(s): CD369 Antigen; Dectin 1; Dectin1
Public MeSH Note: 2026; DECTIN-1 was indexed under LECTINS, C-TYPE 2013-2025, and under MEMBRANE PROTEINS and NERVE TISSUE PROTEINS 2000-2012
History Note: 2026 (2000)
Date Introduced: 2026/01/01
Last Updated: 2026/01/01

Allowable Qualifiers: administration & dosage (AD)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Concept UI: M000768870
Scope Note: A C-type lectin that functions as a pattern recognition receptor on DENDRITIC CELLS and other immune cells. It is specific for beta-1,-linked and beta 1,6-linked GLUCANS that constitute the CELL WALL of pathogenic bacteria and fungi, and is essential for the TOLL-LIKE RECEPTOR 2 INNATE INFLAMMATORY RESPONSE and activation of NF-KAPPA-B.
Terms: Dectin-1 Preferred Term
Term UI T001147671
Date03/25/2025
LexicalTag NON
ThesaurusID NLM (2000); CD369 Antigen
Term UI T001147672
Date03/25/2025
LexicalTag ABX
ThesaurusID NLM (2026); Dectin 1
Term UI T001147673
Date03/25/2025
LexicalTag NON
ThesaurusID NLM (2026); Dectin1
Term UI T001147670
Date03/25/2025
LexicalTag NON
ThesaurusID NLM (2026)

Dectin-1 MeSH Descriptor Data 2026