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Amino Acid Chloromethyl Ketones MeSH Descriptor Data 2025


MeSH Heading
Amino Acid Chloromethyl Ketones
Tree Number(s)
D12.125.065
Unique ID
D000590
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000590
Scope Note
Inhibitors of SERINE ENDOPEPTIDASES and sulfhydryl group-containing enzymes. They act as alkylating agents and are known to interfere in the translation process.
Entry Version
AACK
Entry Term(s)
Peptide Chloromethyl Ketones
Pharm Action
Alkylating Agents
Protein Synthesis Inhibitors
Serine Proteinase Inhibitors
Previous Indexing
Peptides (1966-1976)
specific amino acid (1966-1976)
Public MeSH Note
77; TOSYLLYSINE CHLOROMETHYL KETONE was see under LYSINE 1975-76; TOSYLPHENYLALANYL CHLOROMETHYL KETONE was see under PHENYLALANINE 1975-76
History Note
77
Date Established
1977/01/01
Date of Entry
1976/05/19
Revision Date
1999/11/09
Amino Acid Chloromethyl Ketones Preferred
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